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Real-world observations on neuroinflammation-related drug responses in Alzheimer’s disease. Xu J, Sun A, Yang Y, Shi Y, Lai D, Su J, Li L, Zeng D, Saykin AJ, Cheng F, Liu Y, Zhang P. J Alzheimers Dis. 2025 Nov;108(1):273-280. doi: 10.1177/13872877251376291. Epub 2025 Sep 12. PMID: 40938773 Free PMC article. |
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Longitudinal non-linear changes in the microstructure of the hippocampal subfields in older adults. Zia G, Shahid SS, Yang HC, Gao S, Risacher SL, Saykin AJ, Wu YC. Neurobiol Aging. 2025 Nov;155:113-123. doi: 10.1016/j.neurobiolaging.2025.07.008. Epub 2025 Jul 12. PMID: 40752038 Free PMC article. |
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Plasma proteomic analysis identifies proteins and pathways related to Alzheimer’s risk. Huang YN, Liu S, Park T, Chaudhuri S, Kuchenbecker LA, Carrasquillo MM, Ertekin-Taner N, Bice PJ, Zetterberg H, Blennow K, Russ K, Dage JL, Nudelman KNH, Cruchaga C, Brosch JR, Farlow MR, Clark DG, Mathew S, Unverzagt F, Gao S, Wang S, Apostolova LG, Wilcock DM, Foroud T, Risacher SL, Saykin AJ, Nho K. Alzheimers Dement. 2025 Aug;21(8):e70579. doi: 10.1002/alz.70579. PMID: 40810263 Free PMC article. |
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miR-423-5p and miR-92a-3p in Alzheimer’s disease: relationship with pathology and cognition. Han SW, Park YH, Pyun JM, Bice PJ, Kim S, Saykin AJ, Nho K. Front Aging Neurosci. 2025 Jul 22;17:1637368. doi: 10.3389/fnagi.2025.1637368. eCollection 2025. PMID: 40766177 Free PMC article. |
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Venkatesh R, Cardone KM, Bradford Y, Moore AK, Kumar R, Moore JH, Shen L, Kim D, Ritchie MD. medRxiv [Preprint]. 2025 Jun 2:2025.05.31.25328688. doi: 10.1101/2025.05.31.25328688. Update in: Alzheimers Dement. 2025 Nov;21(11):e70886. doi: 10.1002/alz.70886. PMID: 40502591 Free PMC article. Preprint. |
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Transcriptome analysis of early- and late-onset Alzheimer’s disease in Korean cohorts. Han SW, Hwang J, Park T, Pyun JM, Lee JY, Park JS, Bice PJ, Liu S, Yun S, Jeong J, Risacher SL, Saykin AJ, Byun MS, Yi D, Sung J, Lee DY, Kim S, Nho K, Park YH. Alzheimers Dement. 2025 Feb;21(2):e14563. doi: 10.1002/alz.14563. PMID: 39935412 Free PMC article. |
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Locus coeruleus tau is linked to successive cortical tau accumulation. Yi D, Byun MS, Jung JH, Jung G, Ahn H, Chang YY, Keum M, Lee JY, Lee YS, Kim YK, Kang KM, Sohn CH, Risacher SL, Saykin AJ, Lee DY; KBASE Research Group. Alzheimers Dement. 2025 Feb;21(2):e14426. doi: 10.1002/alz.14426. Epub 2024 Dec 6. PMID: 39641328 Free PMC article. |
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Tau pathway-based gene analysis on PET identifies CLU and FYN in a Korean cohort. Yi D, Byun MS, Park JH, Kim JW, Jung G, Ahn H, Lee JY, Lee YS, Kim YK, Kang KM, Sohn CH, Liu S, Huang YN, Saykin AJ, Lee DY, Nho K; KBASE research group. Alzheimers Dement. 2025 Feb;21(2):e14416. doi: 10.1002/alz.14416. Epub 2024 Dec 3. PMID: 39625110 Free PMC article. |
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LD-informed deep learning for Alzheimer’s gene loci detection using WGS data. Jo T, Bice P, Nho K, Saykin AJ; Alzheimer’s Disease Sequencing Project. Alzheimers Dement (N Y). 2025 Jan 16;11(1):e70041. doi: 10.1002/trc2.70041. eCollection 2025 Jan-Mar. PMID: 39822590 Free PMC article. |
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Multi-Omics Analysis for Identifying Cell-Type-Specific Druggable Targets in Alzheimer’s Disease. Liu S, Cho MY, Huang YN, Park T, Chaudhuri S, Rosewood TJ, Bice PJ, Chung D, Bennett DA, Ertekin-Taner N, Saykin AJ, Nho K. medRxiv [Preprint]. 2025 Jan 9:2025.01.08.25320199. doi: 10.1101/2025.01.08.25320199. Update in: J Transl Med. 2025 Jul 13;23(1):788. doi: 10.1186/s12967-025-06739-1. PMID: 39830273 Free PMC article. Preprint. |
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A DAT1 gene and APOE ε4 interaction is associated with apathy and structural brain changes in mild cognitive impairment and Alzheimer’s disease. Malik R, Beaton D, Ahmed J, Nho K, Saykin AJ, Wang J, Hegele RA, Finger E; Alzheimer’s Disease Neuroimaging Initiative. J Alzheimers Dis. 2025 Jan;103(1):230-242. doi: 10.1177/13872877241299785. Epub 2024 Nov 29. PMID: 39610284 Free PMC article. |
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Cell Type Differentiation Using Network Clustering Algorithms. Nasrollahi FSF, Silva FN, Liu S, Chaudhuri S, Yu M, Wang J, Nho K, Saykin AJ, Bennett DA, Sporns O, Fortunato S. bioRxiv [Preprint]. 2024 Dec 7:2024.12.04.626793. doi: 10.1101/2024.12.04.626793. PMID: 39677670 Free PMC article. Preprint. |
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Association of amyloid and cardiovascular risk with cognition: Findings from KBASE. Chaudhuri S, Dempsey DA, Huang YN, Park T, Cao S, Chumin EJ, Craft H, Crane PK, Mukherjee S, Choi SE, Scollard P, Lee M, Nakano C, Mez J, Trittschuh EH, Klinedinst BS, Hohman TJ, Lee JY, Kang KM, Sohn CH, Kim YK, Yi D, Byun MS, Risacher SL, Nho K, Saykin AJ, Lee DY; KBASE Research Group. Alzheimers Dement. 2024 Dec;20(12):8527-8540. doi: 10.1002/alz.14290. Epub 2024 Nov 7. PMID: 39511852 Free PMC article. |
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TIA1 Mediates Divergent Inflammatory Responses to Tauopathy in Microglia and Macrophages. Webber CJ, van de Spek SJF, Cruz AL, Puri S, Zhang C, Aw JTM, Papadimitriou GZ, Roberts R, Jiang K, Tran TN, Zhang L, Taylor A, Wang Z, Porter J, Sotiropoulos I, Emili A, Silva J, Li H, Wolozin B. bioRxiv [Preprint]. 2024 Nov 7:2024.11.06.622325. doi: 10.1101/2024.11.06.622325. PMID: 39574689 Free PMC article. Preprint. |
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The plasma miRNAome in ADNI: Signatures to aid the detection of at-risk individuals. Kr ger DM, Pena-Centeno T, Liu S, Park T, Kaurani L, Pradhan R, Huang YN, Risacher SL, Burkhardt S, Sch tz AL, Wan Y, Shaw LM, Brodsky AS, DeStefano AL, Lin H, Schroeder R, Krunic A, Hempel N, Sananbenesi F, Blusztajn JK, Saykin AJ, Delalle I, Nho K, Fischer A; Alzheimer’s Disease Neuroimaging Initiative. Alzheimers Dement. 2024 Nov;20(11):7479-7494. doi: 10.1002/alz.14157. Epub 2024 Sep 18. PMID: 39291752 Free PMC article. |
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